Papers & Publications
Acceptability and usability of home-based HIV and blood glucose self-testing and home-based blood pressure measurement in Kenya, South Africa, and Zambia
Oliver, C., Bemer, M., Lauff, A., Morton, J., Cooper, S., Humphries, H., Sharma, H., Pollard, D., Winters, A., van Heerden, A., Bukusi, E., Rech, D., Drain, P. Acceptability and usability of home-based HIV and blood glucose self-testing and home-based blood pressure measurement in Kenya, South Africa, and Zambia. PLOS Global Public Health, Sept 2026
Aimee, an AI-powered HIV prevention and sexual and reproductive health intervention for adolescent girls and young women in South Africa: Design, pilot study methods, and feasibility
Spyrelis A, Frade S, Cooper S et al. Aimee, an AI-powered HIV prevention and sexual and reproductive health intervention for adolescent girls and young women in South Africa: Design, pilot study methods, and feasibility [version 1]. VeriXiv 2026, 3:287 (https://doi.org/10.12688/verixiv.3679.1)
Acceptability, Usability, and Clinical Appropriateness of an AI-Powered Tool for Linkage to HIV Services After HIV Self-Testing in South Africa: Mixed Methods Evaluation
Mahlalela N, Maboa O, Govathson C, Rossouw L, Long L, Greener R, Morris S, Cooper S, Frade S, Pascoe S, Chetty-Makkan C, Acceptability, Usability, and Clinical Appropriateness of an AI-Powered Tool for Linkage to HIV Services After HIV Self-Testing in South Africa: Mixed Methods Evaluation, J Med Internet Res 2026;28:e88570 , DOI: 10.2196/88570
Assessing the role and value of human health workersin the implementation of a digital health solution
L. Rambally Greener, A. Jim, N. Madubela, S. Cooper, S. Malone, “Assessing the role and value of human health workers in the implementation of a digital health solution” , 2026 IAS Conference, Brazil
Demand generation and early engagement with an AI health coach in public clinics in KwaZulu-Natal, South Africa: Insights on uptake and use
L. Rambally Greener, A. Jim, N. Madubela, S. Cooper, S. Malone, “Demand generation and early engagement with an AI health coach in public clinics in KwaZulu-Natal, South Africa: Insights on uptake and use.” , 2026 IAS Conference, Brazil
Rethinking PrEP scale-up: targeting long-acting HIV prevention from everyday conversations
B.M. Segal (University of Oxford, Institute of Biomedical Engineering, UK), S. Morris, R. Mendonca, H. Bekele, Y. Richard, S. Smedinghoff, D. Rech (Audere Africa, Johannesburg SA), W. Delva, C. van Heerden (Katalitix, Cape Town, SA), A. Spyrelis (Shout it Now, Johannesburg, SA), J. Ratevosian (Duke Global Health Institute, USA), “Rethinking PrEP scale-up: targeting long-acting HIV prevention from everyday conversations” , 2026 IAS Conference, Brazil
Feasibility and acceptability of a hybrid AI-human model for HIV prevention among adolescent girls and young women in South African university settings
Solomon Thulare, Paul Potsane, Cleopatra Sokhela, Ntombifikile Mtshali, “Feasibility and acceptability of a hybrid Al-human model for HIV prevention among adolescent girls and young women in South African university settings” , 2026 IAS Conference, Brazil
Rethinking entry and access to care: AI-enabled self-care as HIV service infrastructure
N. Mtshali, A. Spyrelis, D. Rech, P. Potsane, S. Smedinghoff, N. Maricich, S. Cooper, P. Isabelli, W. Delva, D. Roberts, C. van Heerden, S. Morris, N. Tata, S. Frade, A. Anafo, J. Ratevosian, “Rethinking entry and access to care: AI-enabled self-care as HIV service infrastructure” , 2026 IAS Conference, Brazil
From chat to care: turning AI conversations into real-time community intelligence for HIV services
S. Baptiste, B. Segal, J. Ratevosian, K. Gupta, H. Bekele, S. Smedinghoff, R. Mendonca, S. Morris, S. Cooper, D. Rech, A. Spyrelis, P. Potsane, “From chat to care: turning AI conversations into real-time community intelligence for HIV services” , 2026 IAS Conference, Brazil
Co-designing Behavioural Nudges for WhatsApp Social-Network Sharing of an AI-based HIVSupport Tool to Increase HIV Service Utilisation among Underserved Populations in South Africa
Setswe K, Govathson C, Greener R, Pascoe S, Maughan-Brown B, Cooper S, Milford C, Musiello F, Dlamini, B Rambally-Greener L, Madubela N, Malone S, Coetzee L, Chetty-Makkan C, van Heerden A, “Co-designing Behavioural Nudges for WhatsApp Social-Network Sharing of an AI-based HIV Support Tool to Increase HIV Service Utilisation among Underserved Populations in South Africa”, 2026 IAS Conference, Brazil
Rising above misinformation:safety-first, quality-assured AI for HIV and SRH self-care
H. Bekele, R. Mendonca, S. Smedinghoff, J. Alagarajah, S. Cooper, N. Maricich, D. Mbatuegwu, D. Simpson-Cupido, N. Moremi, D. Jaravani, S. Morris, A. Spyrelis, P. Potsane, J. Ratevosian, “Rising above misinformation: safety-first, quality-assured AI for HIV and SRH self-care” , 2026 IAS Conference, Brazil
High-impact digital health tools are built around the human experience, not the technology. Co-design them with users for empathy, trust, choice, and cultural resonance.
Ndumiso Madubela, Letitia Rambally-Greener, Ross Greener, Caroline Govathson, Sophie Pascoe, Candice Chetty-Makkan, Shawn Malone, “High-impact digital health tools are built around the human experience, not the technology. Co-design them with users for empathy, trust, choice, and cultural resonance.” , 2026 IAS Conference, Brazil
Self-Care from Anywhere: Evaluating the usability of an AI-powered HIV toolkit among adolescent girls and young women and healthcare providers in South Africa
Simamkele Bokolo, Caroline Govathson, Laura Rossouw, Sinethemba Madlala, Sasha Frade, Shawna Cooper, Sarah Morris, Sophie Pascoe, Lawrence Long, Candice Chetty-Makkan. Self-Care from Anywhere: Evaluating the usability of an AI-powered HIV toolkit among adolescent girls and young women and healthcare providers in South Africa. medRxiv 2026.04.01.26349925
(pre-print)
Perspectives on App-Assisted Self-Testing Using Rapid Diagnostic Tests Among Community Members, Health Care Providers, and Public Health Leaders in Kenya, South Africa, and Zambia: Qualitative Study
Sharma A, Mwamba C, Maritim P, Humphries H, Kwena Z, Pollard D, O’Malley G, Cooper S, Bemer M, Bukusi E, Lauff A, Naiken L, Madonsela T, Morton J, Rech D, Sang N, Tshazi A, van Heerden A, Winters A, Drain P, Perspectives on App-Assisted Self-Testing Using Rapid Diagnostic Tests Among Community Members, Health Care Providers, and Public Health Leaders in Kenya, South Africa, and Zambia: Qualitative Study, J Med Internet Res 2025;27:e70273, DOI: 10.2196/70273
Breaking barriers: harnessing artificial intelligence for a stigma-free, efficient HIV prevention assessment among adults in South Africa
Govathson C, Chetty-Makkan C, Greener R, Frade S, Rech D, Morris S, Richard Y, Mendonca R, Maricich N, Long L and Pascoe S (2026) Breaking barriers: harnessing artificial intelligence for a stigma-free, efficient HIV prevention assessment among adults in South Africa. Front. Digit. Health 7:1731002. doi: 10.3389/fdgth.2025.1731002
Designing Artificial Intelligence-Powered Health Care Assistants to Reach Vulnerable Populations: A Discrete Choice Experiment Among South African University Students
Amy Zheng MPH , Lawrence Long PhD, Caroline Govathson MSc, Candice Chetty-Makkan PhD, Sarah Morris BS, Dino Rech MBA, Matthew P. Fox DSc , Sophie Pascoe PhD, Designing Artificial Intelligence-Powered Health Care Assistants to Reach Vulnerable Populations: A Discrete Choice Experiment Among South African University Students.Mayo Clinic Proceedings: Digital Health, Volume 3, Issue 3, 2025, 100248, ISSN 2949-7612,https://doi.org/10.1016/j.mcpdig.2025.100248
Online delivery of oral HIV pre- and post-exposure prophylaxis: findings from the ePrEP Kenya pilot
Kiptinness, C., Naik, P., Kareithi, T., Thuo, N., Okello, P., Culquichicon, C., Rafferty, M., Abdulrashid, S., Jomo, E., Nyamasyo, N., Wood, T., Mendonca, R., Malen, R.C., Dettinger, J.C., Pintye, J., Mwangi, J., Stergachis, A., Onentia, J., Curran, K., Mugambi, M.L., Were, D., Ngure, K., Sharma, M., Ortblad, K.F. and (2025), Online delivery of oral HIV pre- and post-exposure prophylaxis: findings from the ePrEP Kenya pilot. J Int AIDS Soc., 28: e26468. https://doi.org/10.1002/jia2.26468
Reimagining HIV prevention with artificial intelligence
Jirair Ratevosian, Michael Reid, Zhao Ni, Rouella Mendonca, Robyn Eakle , Cheryl Johnson, Izukanji Sikazwe, Meshack Ndirangu, Solange Baptiste, Linda-Gail Bekker, “Reimagining HIV prevention with artificial intelligence”, 11 June, 2025, The Lancet HIV, Volume 0, Issue 0
Reform and Renewal: Five Recommendations for PEPFAR
Authors: Ratevosian J, Dow D, Ogbuoji O, Okeke L, Yamey G, Beyrer C; Reviewer: Morris S, "Reform and Renewal: Five Recommendations for PEPFAR" Duke Global Health Institute, Policy Brief, Feb 2025
Generative AI for Health in Low & Middle Income Countries
Hunt I, Parkhouse J, Rich L, Jin K, Imam M, Kim J, Posada M, Lopez M, Ugolnik Z, Soule S, Linos E, "Generative AI for Health in Low & Middle Income Countries" Center for Digital Health, Stanford, April 2025